Ensemble-Based Segmental Helical Organization in an Aib-Rich Lipidated Peptide: Biomacromolecular Insights from High-Field NMR
Biomacromolecules, Article ASAP, published online October 14 (2026).
doi:10.1021/acs.biomac.6c01139Publications
A record of curiosity.
Methods, molecular insights, and the questions that connect them.
Donghan Lee on Google Scholar85 of 85 records
- 2026
- 2026
Enhanced large-scale production and purification of recombinant human NUPR1 for detailed structural and functional insights
Protein Expression and Purification 242, 106940 (2026).
doi:10.1016/j.pep.2026.106940 - 2026
Structural basis of HSL3/NUT receptor kinase-mediated recognition of a disulfide-constrained phytocytokine
Plant Communications 7, 102074 (2026).
doi:10.1016/j.xplc.2026.102074 - 2026
Principal Component Analysis Based Deconvolution of NMR Chemical Shifts for Objective Biomolecular Interaction MappingPALI
Analytical Chemistry 98 (36), 26271–26276 (2026).
doi:10.1021/acs.analchem.6c02780 - 2026
Revealing hidden noncovalent forces of a disulfide bond in protein interactions and biomolecular condensation
International Journal of Biological Macromolecules 351, 151074 (2026).
doi:10.1016/j.ijbiomac.2026.151074 - 2026
ONEST: a web-based platform for the rapid and robust analysis of protein excited states through CEST spectroscopy
Bioinformatics 42 (4), btag158 (2026).
doi:10.1093/bioinformatics/btag158 - 2025
Hierarchically ordered multi-timescale structural dynamics of the intrinsically disordered p53 transactivation domainPreprint
bioRxiv, 2025.08. 01.668138 (2025).
doi:10.1101/2025.08.01.668138 - 2025
A robust, deep learning-based analysis of time-domain signals for NMR spectroscopy
Journal of Analytical Science and Technology 16 (1), 3 (2025).
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An Innovative Inhibitor with a New Chemical Moiety Aimed at Biliverdin IXβ Reductase for Thrombocytopenia and Resilient against Cellular Degradation
Pharmaceutics 16 (9), 1148 (2024).
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Mechanism of methylene blue inducing the disulfide bond formation of tubulin-associated unit proteins
JACS Au 4 (7), 2451 (2024).
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Kinetic evidence in favor of glyoxalase III and against deglycase activity of DJ‐1
Protein Science 32 (5), e4641 (2023).
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Method of increasing platelet counts of a subjectPatent application
US20220339170A1 · Application 17/224,368 (2022).
View patent - 2022
A litmus test for classifying recognition mechanisms of transiently binding proteins
Nature Communications 13 (1), 3792 (2022).
doi:10.1038/s41467-022-31374-5 - 2022
High-power relaxation dispersion NMR data set at different ligand concentrations: a litmus test for classification of recognition mechanism.DatasetLab archive
Edmond, MPDL (2022).
View lab archive - 2022
Repositioning food and drug administration-approved drugs for inhibiting biliverdin ixβ reductase B as a novel thrombocytopenia therapeutic target
Journal of Medicinal Chemistry 65 (3), 2548-2557 (2022).
View on Google Scholar - 2021
A screen of FDA-approved drugs identifies inhibitors of protein tyrosine phosphatase 4A3 (PTP4A3 or PRL-3)
Scientific Reports 11 (1), 10302 (2021).
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Characteristic analysis of homo-and heterodimeric complexes of human mitochondrial pyruvate carrier related to metabolic diseases
International journal of molecular sciences 21 (9), 3403 (2020).
View on Google Scholar - 2020
Identification of small molecules targeting the MdmX-p53 Interaction in Human CancersWithdrawn abstract
Undergraduate Arts and Research Showcase, University of Louisville (2020). Withdrawn in the institutional repository.
View institutional record - 2020
Enhancing NMR derived ensembles with kinetics on multiple timescales
Journal of Biomolecular NMR 74 (1), 27-43 (2020).
View on Google Scholar - 2020
Recombinant expression and purification of AF1q and its interaction with T-cell Factor 7
Protein Expression and Purification 165, 105499 (2020).
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Solution structure and functional investigation of human guanylate kinase reveals allosteric networking and a crucial role for the enzyme in cancer
Journal of Biological Chemistry 294 (31), 11920-11933 (2019).
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pH-responsive delivery of Griffithsin from electrospun fibers
European Journal of Pharmaceutics and Biopharmaceutics 138, 64-74 (2019).
View on Google Scholar - 2018
New methods in biomolecular nuclear magnetic resonance spectroscopy.Lab archive
Methods 138, 1-2 (2018).
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Utilizing dipole-dipole cross-correlated relaxation for the measurement of angles between pairs of opposing CαHα-CαHα bonds in anti-parallel β-sheets
Methods 138, 85-92 (2018).
View on Google Scholar - 2018
1H, 13C and 15N resonance assignment of human guanylate kinase
Biomolecular NMR Assignments 12 (1), 11-14 (2018).
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Solution NMR views of dynamical ordering of biomacromolecules
Biochimica et Biophysica Acta (BBA)-General Subjects 1862 (2), 287-306 (2018).
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NMR methods of characterizing biomolecular structural dynamics and conformational ensembles
Methods 148, 1-3 (2018).
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Simultaneous determination of fast and slow dynamics in molecules using extreme CPMG relaxation dispersion experiments
Journal of Biomolecular NMR 70 (1), 1-9 (2018).
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Label-free NMR-based dissociation kinetics determination
Journal of Biomolecular NMR 69 (4), 229-235 (2017).
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Recent advances in measuring the kinetics of biomolecules by NMR relaxation dispersion spectroscopy
Archives of biochemistry and biophysics 628, 81-91 (2017).
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Kinetics of the Antibody Recognition Site in the Third IgG‐Binding Domain of Protein G
Angewandte Chemie International Edition 55 (33), 9567-9570 (2016).
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High-power 1H composite pulse decoupling provides artifact free exchange-mediated saturation transfer (EST) experiments
Journal of Magnetic Resonance 269, 65-69 (2016).
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Allosteric switch regulates protein–protein binding through collective motion
Proceedings of the National Academy of Sciences 113 (12), 3269-3274 (2016).
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Allostery through protein motion at different length and time scales.Conference abstractLab archive
Biophysical Journal 110 (3), 221a (2016).
View lab archive - 2015
Population shuffling between ground and high energy excited states
Protein Science 24 (11), 1714-1719 (2015).
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Speeding-up exchange-mediated saturation transfer experiments by Fourier transform
Journal of biomolecular NMR 63 (3), 237-244 (2015).
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1H, 13C and 15N resonance assignment of the anti-HIV lectin from Oscillatoria agardhii
Biomolecular NMR assignments 9 (2), 317-319 (2015).
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A combination of spin diffusion methods for the determination of protein–ligand complex structural ensembles
Angewandte Chemie 127 (22), 6611-6615 (2015).
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Sampling of Glycan‐Bound Conformers by the Anti‐HIV Lectin Oscillatoria agardhii agglutinin in the Absence of Sugar
Angewandte Chemie International Edition 54 (22), 6462–6465 (2015).
doi:10.1002/anie.201500213 - 2015
A pre-structured helix in the intrinsically disordered 4EBP1
Molecular BioSystems 11 (2), 366-369 (2015).
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Microsecond motion modulates ubiquitin binding through an allosteric backbone/side chain network.Conference abstractLab archive
Biophysical Journal 108 (2), 184a-185a (2015).
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Population shuffling of protein conformations
Angewandte Chemie International Edition 54 (1), 207-210 (2015).
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A designed conformational shift to control protein binding specificity
Angewandte Chemie 126 (39), 10535-10539 (2014).
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Measuring membrane protein bond orientations in nanodiscs via residual dipolar couplings
Protein Science 23 (7), 851-856 (2014).
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ORIUM: Optimized RDC-based Iterative and Unified Model-free analysis
Journal of biomolecular NMR 58 (4), 287-301 (2014).
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Measuring dynamic and kinetic information in the previously inaccessible supra-τc window of nanoseconds to microseconds by solution NMR spectroscopy
Molecules 18 (10), 11904-11937 (2013).
doi:10.3390/molecules181011904 - 2013
Enhanced accuracy of kinetic information from CT-CPMG experiments by transverse rotating-frame spectroscopy
Journal of biomolecular NMR 57 (1), 73-82 (2013).
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ShereKhan—calculating exchange parameters in relaxation dispersion data from CPMG experiments
Bioinformatics 29 (14), 1819-1820 (2013).
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Molecular recognition through concerted ubiquitin backbone and side chain motion.Conference abstractLab archive
Biophysical Journal 104 (2), 30a (2013).
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Thermal Coefficients of the Methyl Groups within Ubiquitin: 344Conference abstract
Protein Science 21, 190 (2012).
View on Google Scholar - 2012
Determinants of interaction specificity of the Bacillus subtilis GlcT antitermination protein: functionality and phosphorylation specificity depend on the arrangement of the regulatory domains
Journal of Biological Chemistry 287 (33), 27731-27742 (2012).
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Exceeding the limit of dynamics studies on biomolecules using high spin-lock field strengths with a cryogenically cooled probehead
Journal of Magnetic Resonance 221, 1-4 (2012).
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Standard tensorial analysis of local ordering in proteins from residual dipolar couplings
The Journal of Physical Chemistry B 116 (21), 6106-6117 (2012).
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Hyperpolarized binding pocket nuclear overhauser effect for determination of competitive ligand binding
Angewandte Chemie International Edition 51 (21), 5179-5182 (2012).
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Thermal coefficients of the methyl groups within ubiquitin
Protein Science 21 (4), 562-570 (2012).
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Kinetics of conformational sampling in ubiquitin
Angewandte Chemie 123 (48), 11639-11642 (2011).
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Weak long-range correlated motions in a surface patch of ubiquitin involved in molecular recognition
Journal of the American Chemical Society 133 (27), 10336 (2011).
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Dynamic conformational equilibria in the physiological function of the Bombyx mori pheromone-binding protein
Journal of molecular biology 408 (5), 922-931 (2011).
View on Google Scholar - 2010
Detection and Identification of Protein‐Phosphorylation Sites in Histidines through HNP Correlation Patterns
Angewandte Chemie International Edition 49 (47), 8971-8974 (2010).
View on Google Scholar - 2010
Peptide ligands selected with CD4-induced epitopes on native dualtropic HIV-1 envelope proteins mimic extracellular coreceptor domains and bind to HIV-1 gp120 independently of coreceptor usage
Journal of virology 84 (19), 10131-10138 (2010).
View on Google Scholar - 2010
Modular architecture of Munc13/calmodulin complexes: dual regulation by Ca2+ and possible function in short‐term synaptic plasticity
The EMBO journal 29 (3), 680-691 (2010).
doi:10.1038/emboj.2009.373 - 2009
Sensitivity enhancement of methyl-TROSY by longitudinal 1H relaxation optimization
Journal of the Korean magnetic resonance society 13 (1), 15-26 (2009).
doi:10.6564/jkmrs.2009.13.1.015 - 2008
Bilayer in small bicelles revealed by lipid− protein interactions using NMR spectroscopy
Journal of the American Chemical Society 130 (42), 13822-13823 (2008).
View on Google Scholar - 2008
Transverse relaxation-optimized HCN experiment for tautomeric states of histidine sidechains
Journal of the Korean Magnetic Resonance Society 12 (2), 89-95 (2008).
doi:10.6564/jkmrs.2008.12.2.089 - 2007
The structure of receptor‐associated protein (RAP)
Protein science 16 (8), 1628-1640 (2007).
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Structure and interactions of the first three RNA recognition motifs of splicing factor prp24
Journal of molecular biology 367 (5), 1447-1458 (2007).
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The structure of free L11 and functional dynamics of L11 in free, L11-rRNA (58 nt) binary and L11-rRNA (58 nt)-thiostrepton ternary complexes
Journal of molecular biology 367 (4), 1007-1022 (2007).
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NMR assignment of domain 2 of the receptor-associated protein
Journal of Biomolecular NMR 36 (Suppl 1), 54-54 (2006).
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NMR assignment of domain 3 of the receptor-associated protein (RAP)
Journal of Biomolecular NMR 36 (Suppl 1), 56-56 (2006).
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Resonance assignments for the two N-terminal RNA recognition motifs (RRM) of the S. cerevisiae pre-mRNA processing protein Prp24
Journal of Biomolecular NMR 36 (Suppl 1), 58-58 (2006).
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RAP uses a histidine switch to regulate its interaction with LRP in the ER and Golgi
Molecular cell 22 (3), 423-430 (2006).
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Effective rotational correlation times of proteins from NMR relaxation interferenceTRACT
Journal of magnetic resonance 178 (1), 72-76 (2006).
doi:10.1016/j.jmr.2005.08.014 - 2005
Detection of C′, Cα correlations in proteins using a new time-and sensitivity-optimal experiment
Journal of biomolecular NMR 31 (4), 273-278 (2005).
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Unusual heme− histidine bond in the active site of a chaperone
Journal of the American Chemical Society 127 (11), 3716-3717 (2005).
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Polychromatic selective population inversion for TROSY experiments with large proteins
Journal of the American Chemical Society 127 (1), 405-411 (2005).
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NMR structure of the unliganded Bombyx mori pheromone-binding protein at physiological pH
FEBS letters 531 (2), 314-318 (2002).
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Solution structure of the dimeric cytoplasmic domain of syndecan-4
Biochemistry 40 (29), 8471-8478 (2001).
View on Google Scholar - 1999
Crystal structure of Δ5-3-ketosteroid isomerase from Pseudomonas testosteroni in complex with equilenin settles the correct hydrogen bonding scheme for transition state stabilization
Journal of Biological Chemistry 274 (46), 32863-32868 (1999).
View on Google Scholar - 1998
Solution structures of the melanocyte‐stimulating hormones by two‐dimensional NMR spectroscopy and dynamical simulated‐annealing calculations
European journal of biochemistry 257 (1), 31-40 (1998).
doi:10.1046/j.1432-1327.1998.2570031.x - 1998
Solution structure of a syndecan-4 cytoplasmic domain and its interaction with phosphatidylinositol 4, 5-bisphosphate
Journal of Biological Chemistry 273 (21), 13022-13029 (1998).
doi:10.1074/jbc.273.21.13022 - 1998
An influence of the exchange rate on NOE intensities of a ligand: Application to 37kDa trp-holo-repressor/operator DNA complex
Journal of the Korean magnetic resonance society 2 (1), 33-40 (1998).
View on Google Scholar - 1997
A study on the solution structure of α-melanocyte stimulating hormone by NMR spectroscopy.Lab archive
Journal of the Korean Magnetic Resonance Society 1 (1), 45-55 (1997).
View lab archive - 1997
Structural study of horse heart myoglobin by 2D NMR spectroscopy.Lab archive
Journal of the Korean Magnetic Resonance Society 1 (2), 115-124 (1997).
View lab archive - 1997
NMR studies on the hydrogen bonding schemes of Δ⁵-3-ketosteroid isomerase.Lab archive
Journal of the Korean Magnetic Resonance Society 1 (1), 33-44 (1997).
View lab archive - 1994
Nuclear magnetic resonance studies of protein-DNA interactions.Lab archive
Bulletin of the Korean Chemical Society 15, 11-20 (1994).
View lab archive
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Updated October 17, 2026 from Google Scholar, with duplicate records consolidated. The PALI paper is supplemented from ACS Publications. Nine earlier records from the lab archive are retained and labeled. Preprints, conference abstracts, datasets, and patent applications are identified separately. Links use verified DOIs or the source record.